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However, there is a very good chance that if you are reading this article, you have had cortisone injections in the past and you are here looking for options. The fact that new research is pouring in on the detrimental effects of cortisone injections should not convince anyone that suddenly medicine is being alerted to the risk of corticosteroids. The fact that new research is pouring in on the detrimental effects of cortisone injections should not convince anyone that suddenly medicine is being alerted to the risk of corticosteroids. The dangers of cortisone injections have long been known. But in eagerness by health professionals and the patients themselves to get instant relief, the dangers were accepted as part of the treatment, in other words, ‘let’s manage the pain until the patient is ready for joint replacement treatment. In ten years since the evidence has grown. Cortisone can work in the short-term and make the problem worse in the long run. 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